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So far RegenerVate has created 100 blog entries.

BUILDING NEW LIVERS WITH STEM CELL LIVER TREATMENT

By | 2018-09-28T05:49:37+00:00 September 24th, 2018|blog|

Liver disease is on the rise in Canada and one-in-four people might be affected by a liver disease in their lifetime. However, a research team from the University of Edinburgh has created a new stem cell liver treatment to replace damaged liver tissue using lab-grown tissue implants. Using a combination of embryonic stem cells and induced pluripotent stem cells loaded onto 3D tissue scaffolds which encourage stem cells to grow in certain ways, the team implanted the cultured scaffolds into mice with liver disease with highly promising results. "Liver disease is a serious and increasing problemit's currently the fifth biggest killer in the UKand many people with liver disease will die waiting for a transplant or develop complications from the immunosuppressive drugs after a transplant, so we urgently need to find alternatives," lead researcher, [...]

HEALING SPINAL INJURIES WITH LAB-GROWN NEURAL STEM CELLS

By | 2018-09-30T08:59:59+00:00 September 17th, 2018|blog|

A University of California San Diego study has used lab-grown neural stem cells to treat spinal cord injuries in rats for the first time ever. Created from embryonic human pluripotent stem cells (hPSCs) in vitro, the researchers say their revolutionary method provided long-lasting and extensive spinal cord injury recovery in the rats. "Our observations show that these spinal cord NSCs differentiate into a diverse population of spinal cord neurons occupying multiple positions along the dorso-ventral axis, and can be maintained for prolonged time periods," the researchers wrote in Nature Methods. "Grafts into injured spinal cords were rich with excitatory neurons, extended large numbers of axons over long distances, innervated their target structures, and enabled robust corticospinal regeneration." HOW SPINAL CORD INJURIES WORK To understand why this study is important, you need to understand how spinal [...]

DEBUNKING MYTHS ABOUT STEM CELLS

By | 2018-09-28T05:52:39+00:00 September 10th, 2018|blog|

Stem cell research is one of the fastest growing fields of medical science, however, it's still held back by a number of ungrounded myths about stem cells. Most stem cell research controversy stems from these false stem cell myths. Don't be taken in by reactionary media personalities, here are the real facts behind stem cell myths. STEM CELL MYTH 1: STEM CELLS ONLY COME FROM EMBRYOS One of the most nefarious myths about stem cell research, the stem cell research controversy over embryonic stem cells in the mid-2000s caused untold harm to the movement for stem cells across the world. The truth is embryonic stem cells are just one type of stem cells. There are many different types of stem cells and ways to harvest them ranging from blood withdrawals, to bone marrow, to [...]

WHAT’S THE DIFFERENCE BETWEEN REGENERATIVE MEDICINE AND TISSUE ENGINEERING?

By | 2018-09-30T09:00:41+00:00 September 5th, 2018|blog|

Many people believe regenerative medicine and tissue engineering are just different words for the same thing: replacing dead or damaged tissue with biologically engineered replacements. While the two methods share the same goal, they use fundamentally different means to achieve it. TISSUE ENGINEERING Tissue engineering is a process wherein fibroblasts are extracted from a patient and then used to artificially grow cells and tissues in a lab setting using the principles of the body's own tissue growth. This is done using "tissue scaffolds" which encourage cells to develop in a certain way, such as influencing them to grow into bio-artificial bone marrow when implanted under a patient's skin. Using tissue engineering, scientists have been able to create a wide variety of artificial organs including bladders, pancreases, livers, and even whole bones. While the ultimate [...]

THE PROTEIN THAT CAN UNLOCK THE SECRETS OF IPSCS

By | 2018-09-27T09:50:15+00:00 August 27th, 2018|blog|

Since 2006, the cornerstone of many stem cell studies have been induced pluripotent stem cells, or IPSCs. Pluripotent stem cells are essentially immature cells that can differentiate into many different types of cells. Pluripotent stem cells are key to regenerating organs and tissues, however their use was decked in controversy for many years because the main source of them was embryonic stem cells, creating ethical issues lampooned in popular culture like South Park. However, in 2006, Japanese scientist Shinya Yamanaka changed the game with a method that reprogrammed mature cells into a pluripotent form using four growth factors. Yamanaka earned the Nobel Prize for this advancement in 2012, however there have been lingering questions about the transition process and why only 1 out of 1000 cells that are treated successfully convert into an IPSC. But [...]

PRP (PEE R PEE?): THE POWER OF URINE DERIVED STEM CELLS

By | 2018-09-27T09:51:59+00:00 August 20th, 2018|blog|

In 2006, scientists discovered that it was possible to isolate stem cells found within urine and use them to differentiate into different types of autologous cells. When you put aside your natural revulsion, you can see that these types of stem cells have a variety of benefits, since harvesting them is as easy as filling a cup We are now seeing the fruits of this stem cell research into urine derived stem cells. In the past year, there have been a new frontier of stem cell studies into urine derived stem cells with a variety of interesting applications. BUILDING ADRENAL GLANDS At the beginning of the year, researchers from Queen Mary University were able to generate artificial adrenal glands using urine derived stem cells. Adrenal glands produce a variety of important hormones including adrenaline, [...]

3 REVOLUTIONARY STEM CELL STUDIES ON THE HORIZON

By | 2018-09-30T10:22:22+00:00 August 13th, 2018|blog|

Every day, scientists are working to make the future better by testing the reaches of the almost limitless potential of stem cells. It seems like every there's constantly news about the latest advances in stem cell research, but here are the three upcoming stem cells studies we think you should keep your eyes out for. SAVING THE NORTHERN WHITE RHINO WITH STEM CELL RESEARCH The staff at the Leibniz Institute for Zoo and Wildlife Research are gearing up for a stem cell studystraight out of Jurassic Park. They plan to bring the Northern White Rhino back from the edge of extinction by using induced pluripotent stem cells to facilitate the in-vitro fertilization of the last two surviving female Northern White Rhinos with hybrid embryos cultivated from Southern White Rhino eggs fertilized with Northern White Rhino [...]

STEM CELLS, PRP & SPORT INJURY: THE BEST METHOD OF RECOVERY?

By | 2018-09-27T09:57:09+00:00 August 7th, 2018|blog|

In 2011, Indiana Colts quarterback Peyton Manning had to sit out the whole season due to a serious neck injury that required two major surgeries to treat. While the Colts released Manning during his recovery, he made his return to the field in 2012 with the Denver Broncos with a stunning comeback season that saw him make 37 touchdowns and 11 interceptions, earning him the title of NFL Comeback Player of the Year. He would go on to play three more seasons with the Broncos, crowning his final season in 2015 with his second Super Bowl title at the ripe age of 39, making him the oldest starting quarterback in league history to do so. Later on, it was revealed that there was a secret to his post-injury success. In between his surgeries, Manning [...]

MSCS AND WEIGHT LOSS: READY FOR HUMAN TRIALS?

By | 2018-09-30T09:12:18+00:00 July 23rd, 2018|blog|

The diet industry makes billions of dollars a year feeding off people's insecurities with scientifically dubious medications and nutritional regimes. Even methods that are successful in causing weight loss are ultimately proven futile because the subject reverts back to old habits and regains the weight. However, a number of stem cell research studies in animals over the years have found that mesenchymal stem cells (or MSCs) have the capacity to fight obesity with regenerative medicine, because in a way, they're part of the problem. MSCs develop into adipocyte, which are the fat cells that make up the adipose tissue that stores energy in the form of fat. By looking into mesenchymal stem cells' role in adipocyte generation, many scientists believe non-invasive stem cell treatments and stem cell therapy to treat obesity could be developed. [...]

HOW PLURIPOTENT STEM CELLS CAN HELP PREDICT DISEASE

By | 2018-09-27T10:02:41+00:00 July 17th, 2018|blog|

The human genome might be mapped, but there are still many spots that say "Here be Dragons," especially when you try to determine if variants found in genetic sequencing will lead to diseases. However, a novel study from the Stanford Cardiovascular Institute has found a way to narrow down genetic "variants of uncertain significance" to find out just what kind of health problems they can cause, by using induced pluripotent stem cells. WHAT ARE PLURIPOTENT STEM CELLS AND IPSCS? Pluripotent stem cells are the most dynamic types of stem cells, capable of differentiating into cells of any the body's three layers (ectoderm, ectoderm, and mesoderm). However, the cost to this flexibility is that they are also the least numerous form of stem cells, primarily found in embryos. However, the solution scientists have come up [...]