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Can Stem Cells Offer Stroke Patients Renewed Hope?

Posted by Douglas W. Stoddard MD, M Sp Med, Dip Sport Med, ES on 5 March 2018
Can Stem Cells Offer Stroke Patients Renewed Hope?

A stroke occurs when blood flow and oxygen are cut off to the brain, adversely damaging brain cells that control parts of the body.

Strokes effect 800,000 people every year in the US, killing 140,000 as a result.

There are many lifestyle risk factors that leave individuals more vulnerable to a stroke obesity, inactivity, binge drinking, and use of illicit substances. Medical risk factors include high cholesterol, diabetes, sleep apnea, high blood pressure, and cardiovascular disease.

Depending on the severity of a stroke, victims can experience muscle weakness, numbness, pressure sores, pneumonia, incontinence, apraxia, appetite loss, speech loss, and vision loss.

Since major stroke survivors are typically severely disabled during their recovery, they struggle to carry out simple tasks. For those lucky enough to make a full recovery, the process is long and painful.

But thanks to recent stem cell research, there may be way to help the brain heal faster.

Stem Cell Stealth

In a previous study, a set of CD34+ stem cells were utilized in triggering the growth of new brain tissue and blood vessels. These stem cells are also known as progenitor cells, and are multipotent, meaning they self-renew for long periods of time & differentiate into specialized cells with specific functions.

A few years later, another study restored mobility in the limbs of stroke victims by injecting stem cells into their brains.

Recently, the University of Georgia's Regenerative Bioscience Center and ArunA Biomedical have taken the next step in applying stem cells to expedite stroke recovery.

They've embarked on a study using tube-shaped structures generated by neural stem cells known as exosomes. Exosomes are smaller than cells, providing a stealth-like quality that allows them to cross barriers that cells can't, allowing them to deliver multiple doses of regenerative medicine to ailing areas.

Researchers believe that, when applied in tandem with other therapies, AB126 will change cell progression and improve functional recovery.

Minimizing the Damage

The AB126 treatment improved the recovery of motor control and memory in mouse test subjects.

When comparing MRI scans of AB126-treated mice to other untreated stroke-afflicted animals, the team found that the treatment shrunk the size of the injury by about 35%. It also preserved half of the brain tissue usually lost after a stroke.

The team saw improved mobility, balance, and behavioral benefits within days in the treated animal models.

The researchers found similar results when testing on pigs, and are now preparing for human studies in 2019.


While we aren't offering groundbreaking stem cell therapy to recovering stroke patients, we are administering state-of-the-art stem cell and PRP injections to treat chronic pain conditions.

If you're struggling from osteoarthritis, plantar fasciitis, tendonitis, meniscal tears, tenosynovitis, or any other chronic pain, RegenerVate's regenerative therapies may be for you. Instead of putting you under the knife, our non-invasive injection therapies use your body's own healing properties to expedite recovery from aches, pains, tears, and breaks.

Contact us so we can help you naturally alleviate your aches & pains!
 

Author: Douglas W. Stoddard MD, M Sp Med, Dip Sport Med, ES
About: Dr. Stoddard is a sport medicine and injection physician in Toronto and is the Medical Director of RegenerVate. After receiving his medical degree from the University of Toronto, he trained in Australia at the Australian Institute of Sport in Canberra, obtaining his Master Degree in Sport Medicine. His injection training, including ultrasound, PRP and Prolotherapy, was primarily done in the USA. He is a diplomat of the Canadian Academy of Sport and Exercise Medicine (CASEM), is married and a proud father of two boys. He is an avid triathlete and occasional guitar player.
Tags: Stem Cell Research

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